1st Prague Protein’s Spring
Program
Thursday, May 6, 2010
5:00 PM - 8:00 PM
Registration
8:00 PM - 10:00 PM
Welcome drink
Friday, May 7, 2010
8:30 – 8:40
Introduction, welcome speach
SESSION 1: Peptides
chairman Valerie Dagett
8:40 – 9:20
Pavel Hobza, CZ
Energy minima and transition structures on potential energy surface of polypeptides
9:20 – 10:00
Daniel Fitz, AU
Peptide Evolution and its Consequences for Amino Acid Sequences and Biohomochirality
10:00 – 10:40
Massimiliano Bonomi, CH
(Extending) metadynamics: accurate free energy reconstruction and comparison with experiments.
10:40 – 11:00
Coffee Break
11:00 – 11:40
Valerie Daggett, USA
Dynameomics
11:40 – 12:20
Emmanuele Paci, UK
Thermodynamics, kinetics and mechanics of structured and unstructured polypeptides
12:20 – 14:00 Lunch
Afternoon
SESSION 2: Protein Folding
Chairman Michele Vendruscolo
14:00 – 14:40
Michele Vendruscolo, UK
Determination of protein structure and dynamics from sparse NMR data
14:40 – 15:20
Patricia Clark,USA
Pausing and Folding During Translation
15:20 – 16:00
Vladimir Sklenar, CZ
The N-terminal Domain of Mason-Pfizer Monkey Virus Capsid Protein:Structure,Function and Dynamics
16:00 – 16:30
Coffee Break
16:30 – 17:10
Pavel Jungwirth, CZ
Ions at surfaces of hydrated proteins and their components
17:10 – 17:50
Angel Garcia, USA
Microsecond simulations of the detailed folding/unfolding thermodynamics of proteins under various solvent conditions
18:00 – 20:00 dinner
20:00 – 23:00 Poster Session
Saturday, May 8, 2010
SESSION: Protein Folding and Protein Interactions
chairman Mikael Oliveberg
8:30 – 9:10
Michael Oliveberg, S
Folding-induced ion transfer in the ALS-associated enzyme SOD1
9:10 – 9:50
Stephano Gianni, I
Understanding the folding problem by studying protein families and circular permutants
9:50 - 10:30
Bojan Zagrovic, AU
Studying protein-protein interactions using computer simulations: from specific effect to protein ecology
10:30 – 11:00
Coffee Break
11:00 – 11:40
Steven Homans, UK
Ligand -Protein Interactions: some surprises.
11:40 – 12:20
Jacques Chomilier, F
Prediction of the protein folding nucleus from Monte Carlo simulations
12:20 – 15:00 Lunch
SESSION: Protein Disorder and Protein Aggregation
chairman Amedeo Caflisch
15:00 – 15:40
Feng Ding, USA
Engineering allosteric regulation of proteins
15:40 – 16:20
Nobuhiko Tokuriki, UK
The stability effect of mutation and protein evolution
16:20 – 17:00
Amedeo Caflisch, CH
Simulations of amyloid aggregation
17:00 – 17:30
Coffee Break
17:30 – 18:10
Peter Tompa, H
Structural disorder and aberrant proteins in the cell
18:10 – 19:00
Madan M. Babu, UK
Intrinsically Unstructured Proteins: Regulation and Disease
19:00 – 19:05
Concluding remarks
19:30 -22:00
Dinner at traditional Czech pub
